HomeBanques de composésPyroptosis Compound Library

Pyroptosis Compound Library

N° de cat.L7400

Une collection unique de 751 composés liés à la pyroptose utilisés pour le criblage à haut débit (HTS) et le criblage à haut contenu (HCS).

96 well plates

Personnalisez votre bibliothèque :

Cité par 327 Publications

Pyroptosis Compound Library Contenu

Description et avantages

•Pyroptosis is a form of necrotic and inflammatory programmed cell death mediated by the activation of caspase-1.Pyroptosis is widely involved in the occurrence and development of infectious diseases, nervous system related diseases and atherosclerotic diseases.Recent studies have shown that pyroptosis can enhance anti-tumor immunity;
 
•A unique collection of 751 pyroptosis related compounds used for high throughput screening(HTS) and high content screening(HCS);
 
•Some compounds have been approved by the FDA;
 
•Structurally diverse,medicinally active,and cell permeable;
 
•Rich documentation with structure and bioactivity information;
 
•NMR and HPLC validated to ensure high purity.

Détails du produit

Formulation 704 compounds pre-dissolved in 10mM DMSO, 25 compounds pre-dissolved in 10mM water, 20 compounds pre-dissolved in 2mM DMSO and 2 compounds pre-dissolved in 2mM water
Récipient Plaque à 96 puits profonds scellée avec du papier daluminium
Stabilité 12 months -20°C in DMSO
24 months -80°C in DMSO
Expédition Glace bleue ou glace sèche

Études de cas utilisant les bibliothèques de composés Selleck

Pyroptosis Compound Library Composition

Partenaires dinstallations HTS

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania