Histone modification compound library

N° de cat.L4900

Une collection unique de 347 petits composés moléculaires avec une activité biologique utilisés pour la recherche sur la modification des histones et les essais associés.

96 well plates

Personnalisez votre bibliothèque :

Cité par 321 Publications

Description et avantages

• A unique collection of 347 small molecule compounds for high throughput screening(HTS) and high content screening (HCS).
 
• A useful tool for histone modification research and associated assays
 
• Targets Epigenetic Reader Domain, HDAC, Histone Methyltransferase, Histone Demethylase and Histone Acetyltransferase
 
• For studying human diseases, exploring the pathogenesis of diseases
such as cancer, and opening noval therapeutic ways 
 
• Structurally diverse, medicinally active, and cell permeable
 
• Rich documentation with structure description, target information, IC50
 values and customer reviews
 
• NMR and HPLC validated to ensure high purity

 

Détails du produit

Formulation 337 compounds pre-dissolved in 10mM DMSO, 2 compound pre-dissolved in 10mM water and 8 compounds pre-dissolved in 2mM DMSO
Récipient Plaque à 96 puits profonds scellée avec du papier daluminium
Stabilité 12 months -20°C in DMSO
24 months -80°C in DMSO
Expédition Glace bleue ou glace sèche

Études de cas utilisant les bibliothèques de composés Selleck

Histone modification compound library Composition

Partenaires dinstallations HTS

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania