HomeBanques de composésProtein-protein Interaction Inhibitor Library

Protein-protein Interaction Inhibitor Library

N° de cat.L8100

Une collection unique de 407 inhibiteurs d'interaction protéine-protéine (IPP) utilisés pour le criblage à haut débit (HTS) et le criblage à haut contenu (HCS).

96 well plates

Personnalisez votre bibliothèque :

Cité par 321 Publications

Protein-protein Interaction Inhibitor Library Contenu

Description et avantages

•Protein-protein interactions (PPI) represent a vast class of therapeutic targets both inside and outside the cell.Inhibitors of a number of protein–protein interactions (PPIs) have emerged as potential anticancer drug candidates; 
 
•A unique collection of 407 protein-protein Interaction(PPI) Inhibitors used for high throughput screening(HTS) and high content screening(HCS);
 
•Targets PD-1/PD-L1, BCL family, Bromodomains, MDM2, HIV integrase, etc.  
 
•Some compounds have been approved by the FDA;
 
•Structurally diverse,medicinally active,and cell permeable;
 
•Rich documentation with structure and bioactivity information;
 
•NMR and HPLC validated to ensure high purity.       

Détails du produit

Formulation 384 compounds pre-dissolved in 10mM DMSO, 12 compounds pre-dissolved in 10mM water, 9 compounds pre-dissolved in 2mM DMSO and 2 compounds pre-dissolved in 2mM water
Récipient Plaque à 96 puits profonds scellée avec du papier daluminium
Stabilité 12 months -20°C in DMSO
24 months -80°C in DMSO
Expédition Glace bleue ou glace sèche

Études de cas utilisant les bibliothèques de composés Selleck

Protein-protein Interaction Inhibitor Library Composition

Partenaires dinstallations HTS

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania