Home MAPK S6 Kinase p70 S6K1-Sélectif Inhibitors

p70 S6K1-Sélectif Inhibitors

  • p70 S6K
  • p70 S6K1
  • RSK1
  • RSK2
  • RSK3
  • RSK4
N° Cat. Nom du produit Information Sélectif / Pan IC50 / Ki
S2163 PF-4708671 PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 than MSK1 and RSK1/2, respectively. First S6K1-specific inhibitor to be reported. Selective p70 S6K1, IC50: 160 nM